Hydrophilic Interaction Liquid Chromatography-Electrospray Ionization Mass Spectrometry for Therapeutic Drug Monitoring of Metformin and Rosuvastatin in Human Plasma

In this work a hydrophilic interaction liquid chromatography/positive ion electrospray mass GF COCONUT SHRED UNSWT spectrometric assay (HILIC/ESI-MS) has been developed and fully validated for the quantitation of metformin and rosuvastatin in human plasma.Sample preparation involved the use of 100 μL of human plasma, following protein precipitat

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First report of concurrent mixed germs induced destructive emphysematous pyelonephritis and emphysematous endophthalmitis in the patient with COVID-19

A 35-year-old diabetic woman was referred Left Thumb Switch Heartrate Grip to the emergency department with fever, left flank pain, pneumaturia, and impaired vision of the left eye from 4 days ago.Fever, tachycardia, tachypnea, low blood pressure, metabolic acidosis, and azotemia were the first findings.The diagnosis was a coincidence of emphysemat

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